Cellular response to collagen-elastin composite materials
نویسندگان
چکیده
منابع مشابه
Reversibly assembled cellular composite materials.
We introduce composite materials made by reversibly assembling a three-dimensional lattice of mass-produced carbon fiber-reinforced polymer composite parts with integrated mechanical interlocking connections. The resulting cellular composite materials can respond as an elastic solid with an extremely large measured modulus for an ultralight material (12.3 megapascals at a density of 7.2 milligr...
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The annually necessary human bone grafts are in continuous grown due to the increasing of fractals, congenital and non-congenital diseases. Based on statistical reports (Murugan and Ramakrishna 2005), only in USA about 6.3 million fractures occur every year and about 550.000 of these require bone grafting. The most frequently fractures occur at the level of hip, ankle, tibia and fibula. Due to ...
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PROCOLLAGEN-COLLAGEN CONVERSION The first extracellular step after secretion is the proteolytic cleavage of these Nand C-terminal nonhelical regions of procollagen (Bornstein, 1974). The actual location of cleavage of these extension peptides is not known, but they are probably removed during the formation of the fibre and may take part in fibrogenesis. The intermediates in the conversion of pr...
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Adv. Mater. 2010, 22, 2041–2044 2010 WILEY-VCH Verlag G T IO N Emerging biomaterials based upon analogues of native extracellular matrix proteins provide an opportunity to create protein scaffolds that mimic tissue mechanical behavior and guide cellular responses. However, in order to reproduce macroscale tissue properties, protein analogues must be endowed with appropriate microstructural feat...
متن کاملHierarchically biomimetic bone scaffold materials: nano-HA/collagen/PLA composite.
A bone scaffold material (nano-HA/ collagen/PLA composite) was developed by biomimetic synthesis. It shows some features of natural bone both in main composition and hierarchical microstructure. Nano-hydroxyapatite and collagen assembled into mineralized fibril. The three-dimensional porous scaffold materials mimic the microstructure of cancellous bone. Cell culture and animal model tests showe...
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ژورنال
عنوان ژورنال: Acta Biomaterialia
سال: 2019
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2018.12.033